Nowadays, companies aim to achieve a competitive advantage among their competitors and gain customer satisfaction. They have started to use enterprise resource planning (ERP) systems with the goal of improving business performance This paper provides a framework for comparison between the in-house implementation of ERP systems versus the in-cloud implementations. The paper first establishes a framework for the comparison based on three factors: pre-live, i.e., the implementation methodologies of both options; post-live, i.e., cost, time and the user-friendliness of the systems; and other factors, i.e., security and scalability. Results show that in-cloud systems are faster to implement, less costly and easier to use and scalable. In-house system, compared with in-cloud, gives organizations more control and hence many organizations more secure.