This book constitutes the refereed post-conference proceedings of the Second International Conference on ICT for Health, Accessibility and Wellbeing, IHAW 2022, held in Larnaca, Cyprus, in December 2022. The revised 14 full papers and 3 short papers presented were carefully selected from 33 submissions. The papers are thematically arranged in the following sections: Visual Impairment and ICT for Mobility; ICT and Student Health; ICT and Wellbeing and ICT & Health prevention