This book describes the control loop-oriented change management process for implementing a digital business model via the holistic Organization 4.0 MITO configuration management. The content chapter structure of this MITO book with the description of the different transformation design views is based on the higher-level operational control loop principle within the MITO model segments shown in Figure 1. Whereby the management segment (M) is still subdivided on the default side into the process-related management segment and on the feedback side into the fact-related management segment. The MITO business model based on this supplements the 5 model segments with the downstream customer and upstream supplier segments and integrates the hierarchical process level model into the MITO model representation for the conception of the process-oriented target, management and control system. This book is a translation of the original German 1st edition Ganzheitliche Businessmodell-Transformation by Hartmut F. Binner, published by Springer Fachmedien Wiesbaden GmbH, part of Springer Nature in 2020. The translation was done with the help of artificial intelligence (machine translation by the service DeepL.com). A subsequent human revision was done primarily in terms of content, so that the book will read stylistically differently from a conventional translation. Springer Nature works continuously to further the development of tools for the production of books and on the related technologies to support the authors.