This book constitutes the refereed proceedings of the 32nd International Symposium on Logic-Based Synthesis and Transformation, LOPSTR 2022, which was held during September 21-23, 2022. The 8 full papers were selected from 17 submissions and cover different aspects of logic-based program development, all stages of the software life cycle, and issues of both programming-in-the-small and programming-in-the-large.