This book constitutes the proceedings of the 13th International Conference on Swarm Intelligence, ANTS 2022, held in Málaga, Spain, in November 2022. The 19 full papers presented, together with 14 short papers and 4 extended abstracts were carefully reviewed and selected from 45 submissions. ANTS 2022 contributions are dealing with any aspect of swarm intelligence such as behavioral models of social insects, empirical and theoretical research in swarm intelligence, application of swarm intelligence methods, and much more.