This volume constitutes selected papers presented at the First International Conference on Emerging Technology Trends in IoT and Computing, TIOTC 2021, held in Erbil, Iraq, in June 2021. The 26 full papers were thoroughly reviewed and selected from 182 submissions. The papers are organized in the following topical sections: Internet of Things (IOT): services and applications; Internet of Things (IOT) in healthcare industry; IOT in networks, communications and distributed computing; real world application fields in information science and technology.