This book constitutes the refereed conference proceedings of the 4th International Conference on Emerging Technologies in Computing, iCEtiC 2021, held in August 2021. Due to VOVID-19 pandemic the conference was helt virtually. The 15 revised full papers were reviewed and selected from 44 submissions and are organized in topical sections covering Information and Network Security; Cloud, IoT and Distributed Computing; AI, Expert Systems and Big Data Analytics