This book constitutes the refereed post-conference proceedings of the 15th EAI International Conference on Quality, Reliability, Security and Robustness in Heterogeneous Networks, QShine 2020, held in November 2020. Due to COVID-19 pandemic the conference was held virtually. The 19 revised full papers were carefully reviewed and selected from 49 submissions. The papers are organized thematically in tracks on Network Reliability and Security an Emerging Applicationscourse for computer science and engineering students, as well as a reference manual for researchers and developers.