This book constitutes extended, revised and selected papers from the 7th International Conference on Optimization Problems and Their Applications, OPTA 2018, held in Omsk, Russia in July 2018. The 27 papers presented in this volume were carefully reviewed and selected from a total of 73 submissions. The papers are listed in thematic sections, namely location problems, scheduling and routing problems, optimization problems in data analysis, mathematical programming, game theory and economical applications, applied optimization problems and metaheuristics.