This introduction article lays out a path for successful business innovation, based on several successful practices in several industries. In order to successfully build businesses, companies have to understand the game changing trends in the networked economy where ubiquitous connectivity opens up new opportunities but technologies become commodities. Connected business initiatives are based on business value which has to be distributed between the customers, the partners in the ecosystem, and the own company. To achieve competitive advantage, data-based business models around the customer journeys, end-to-end solutions, and the ability to partner in a dynamic coopetition world play an important role.