These contributions, written by the foremost international researchers and practitioners of Genetic Programming (GP), explore the synergy between theoretical and empirical results on real-world problems, producing a comprehensive view of the state of the art in GP. Chapters in this volume include: Similarity-based Analysis of Population Dynamics in GP Performing Symbolic Regression Hybrid Structural and Behavioral Diversity Methods in GP Multi-Population Competitive Coevolution for Anticipation of Tax Evasion Evolving Artificial General Intelligence for Video Game Controllers A Detailed Analysis of a PushGP Run Linear Genomes for Structured Programs Neutrality, Robustness, and Evolvability in GP Local Search in GP PRETSL: Distributed Probabilistic Rule Evolution for Time-Series Classification Relational Structure in Program Synthesis Problems with Analogical Reasoning An Evolutionary Algorithm for Big Data Multi-Class Classification Problems A Generic Framework for Building Dispersion Operators in the Semantic Space Assisting Asset Model Development with Evolutionary Augmentation Building Blocks of Machine Learning Pipelines for Initialization of a Data Science Automation Tool Readers will discover large-scale, real-world applications of GP to a variety of problem domains via in-depth presentations of the latest and most significant results.