One-Step Generation of a Drug-Releasing Microarray for High-Throughput Small-Volume Bioassays
Seo Woo Song
Informasi Umum
Kode
21.21.544
Klasifikasi
615.321 - Drugs derived from plants, Herbal medicine, Herbals, Medicinal plants, Minimally processed alkaloids, Pharmacognosy, Crude drugs and simples
Jenis
Buku - Elektronik (E-Book)
Subjek
Biological And Medical Physics, Microarray, Drug Releasing, Encoded Drug-laden Microparticle
No. Rak
Tel-U Gedung Manterawu Lantai 5 : Rak 11b
Tel-U Purwokerto : Rak 6
Dilihat
53 kali
Informasi Lainnya
Abstraksi
This thesis demonstrates a technology that enables pipetting-free high-throughput screening (HTS) on a miniaturized platform, eliminating the need for thousands of one-by-one pipetting and conventional liquid handling systems. This platform enhances accessibility to HTS and enables HTS to be used in small-to-medium scale laboratories. In addition, it allows large-scale combinatorial screening with a small number of valuable cells, such as patients’ primary cancer cells. This technique will have a high impact on the widespread use of HTS in the era of personalized medicine.
In this thesis, the author firstly describes the need and concept of ‘part petting for pipetting-free HTS platform. It is realized by the one-step pipetting and self-assembly of encoded drug-laden microparticles (DLPs) on the microwells. Next, the technical implementations required for the platform demonstration are described. It includes the preparation of encoded DLPs, plastic chip fabrication, and the realization of an automated system. Lastly, screening of sequential drug combinations using this platform is demonstrated. This shows the potential of the proposed technology for various applications.
- TUI1A3 - FISIKA 1
- EBG4B3 - INSTRUMENTASI BIOMEDIS
- EBH4A3 - FISIKA BIOMEDIKA
- TFI3L1 - PRAKTIKUM TEKNIK FISIKA 4
- TUI1F3 - FISIKA 2
- TUI1A1 - PRAKTIKUM FISIKA 1
- TUI1F1 - PRAKTIKUM FISIKA 2
- TFI2K1 - PRAKTIKUM TEKNIK FISIKA 1
- TFI2L1 - PRAKTIKUM TEKNIK FISIKA 2
- TFI3F1 - PRAKTIKUM TEKNIK FISIKA 3
- EBG4A3 - FISIKA BIOMEDIS
- TUI1A3 - FISIKA 1
- TUI1F3 - FISIKA 2
- TBI2B3 - FISIKA BIOMEDIS
- TUI1A1 - PRAKTIKUM FISIKA 1
- TUI1F1 - PRAKTIKUM FISIKA 2
- AEK2BAB3 - Fisika Biomedis
- AZK1BAB3 - Fisika 1
- AZK1GAB3 - Fisika 2
- AZK1CAB1 - Praktikum Fisika 1
- AZK1HAB1 - Praktikum Fisika 2
- AZK1BAB3 - Fisika 1
- AZK1GAB3 - Fisika 2
- AZK1CAB1 - Praktikum Fisika 1
- AZK1HAB1 - Praktikum Fisika 2
Koleksi & Sirkulasi
Tersedia 1 dari total 1 Koleksi
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Pengarang
| Nama | Seo Woo Song |
| Jenis | Perorangan |
| Penyunting | |
| Penerjemah |
Penerbit
| Nama | Springer Singapore |
| Kota | Singapore |
| Tahun | 2019 |
Sirkulasi
| Harga sewa | IDR 0,00 |
| Denda harian | IDR 0,00 |
| Jenis | Non-Sirkulasi |
